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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Geoff Zahn SP | 1 | 2 | 1 | 3.38 | 10 | 0 | 13.1 | 16 | 6 | 5 | 1 | 5 | 10 | 1.57 | .291 | .341 | 0.1 |
| Stephen Strasburg SP | 16 | 11 | 0 | 3.43 | 34 | 34 | 241.2 | 239 | 98 | 92 | 30 | 56 | 202 | 1.22 | .257 | .298 | 3.5 |
| Glen Perkins CL | 6 | 6 | 24 | 3.69 | 53 | 0 | 53.2 | 50 | 26 | 22 | 6 | 24 | 51 | 1.38 | .239 | .286 | 0.7 |
| Pete Dowling SP | 16 | 10 | 0 | 3.78 | 34 | 34 | 252.2 | 230 | 114 | 106 | 24 | 111 | 190 | 1.35 | .242 | .277 | 2.3 |
| Ron Davis CL | 2 | 4 | 2 | 3.80 | 27 | 0 | 45.0 | 39 | 26 | 19 | 7 | 16 | 48 | 1.22 | .225 | .269 | -0.0 |
| Pete Redfern SP | 3 | 1 | 0 | 3.98 | 13 | 6 | 54.1 | 47 | 25 | 24 | 5 | 22 | 60 | 1.27 | .228 | .292 | 1.0 |
| John Lackey SP | 14 | 16 | 0 | 4.20 | 34 | 34 | 220.2 | 219 | 118 | 103 | 17 | 79 | 172 | 1.35 | .259 | .305 | 2.8 |
| Owen Scheetz RP | 0 | 1 | 0 | 4.24 | 24 | 0 | 40.1 | 49 | 24 | 19 | 2 | 17 | 20 | 1.64 | .297 | .326 | 0.2 |
| Steve Renko SP | 8 | 19 | 0 | 4.62 | 34 | 34 | 222.0 | 254 | 127 | 114 | 35 | 61 | 186 | 1.42 | .286 | .323 | 1.9 |
| Eric Erickson SP | 2 | 7 | 2 | 4.88 | 37 | 9 | 127.1 | 123 | 77 | 69 | 21 | 57 | 124 | 1.41 | .255 | .297 | -0.1 |
| Tim Mauser RP | 1 | 1 | 1 | 6.52 | 11 | 0 | 19.1 | 22 | 16 | 14 | 0 | 16 | 17 | 1.97 | .278 | .349 | 0.1 |
| Gio Gonzalez SP | 2 | 3 | 2 | 7.38 | 31 | 3 | 61.0 | 80 | 54 | 50 | 9 | 36 | 56 | 1.90 | .315 | .368 | -0.5 |
| Roger Nelson SP | 2 | 0 | 0 | 7.88 | 5 | 0 | 8.0 | 13 | 10 | 7 | 3 | 2 | 6 | 1.88 | .351 | .333 | -0.3 |
